Toxicological studies of acetone extract of moringa oliefera lam. roots

ABSTRACT

Plants and their metabolities play a key role in community health. The data of the acute toxicity is obligatory in order to verify the safety profile of plant extracts. The aim of this work was to study the effects of Moringa oleifera root acetone extract [MRA] administrated orally to NMRI mice [n=6] daily for 7 consecutive days at a dose of 700mg/kg, while control animals [n=6] received Tween-80 [5%]. Physical parameters and histopathological studies were observed for any organ specific toxicities in liver, heart, kidney, spleen and lungs. M. oleifera root acetone extract [700 mg/kg] was non-toxic in mice