Serum Antibodies against Helicobacter pylori Neutrophil Activating Protein in Carriers of IL-4 C-590T Genetic Polymorphism Amplify the Risk of Gastritis and Gastric Cancer
IBJ-Iranian Biomedical Journal. 2017; 21 (5): 321-329
Dans Anglais
| IMEMR
| ID: emr-188489
ABSTRACT
Background:
Gastric cancer arises, mainly, on an inflammatory background. Helicobocter pylori neutrophil activating [HP-NAP] protein functions as a potent pro-inflammatory mediator. Similarly, IL-4 plays a critical role in the inflammation pathway, the levels of which are altered by C to T transition at position -590 in its promoter region. Here, we have aimed to assess the risk of gastritis and gastric cancer in the co-presence of these two inflammation modulating mediators
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Polymorphisme génétique
/
Études prospectives
/
Helicobacter pylori
/
Interleukine-4
/
Activation des neutrophiles
/
Gastrite
/
Iran
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Iran. Biomed. J.
Année:
2017
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