Multiplex-polymerase chain reaction for detecting microdeletions in the azoospermia factor region of Y chromosome in Iranian couples with non-obstructive infertility and recurrent pregnancy loss
IJFS-International Journal of Fertility and Sterility. 2018; 11 (4): 253-257
Dans Anglais
| IMEMR
| ID: emr-191356
ABSTRACT
Background:
Approximately 15% of couples are infertile with the male factor explaining approximately 50% of the cases. One of the main genetic factors playing a role in male infertility is Y chromosomal microdeletions within the proximal long arm of the Y chromosome [Yq11], named the azoospermia factor [AZF] region. Recent studies have shown there is a potential connection between deletions of the AZF region and recurrent pregnancy loss [RPL]. The aim of this study is to examine this association by characterizing AZF microdeletions in two infertile groups in men with non-obstructive infertility and in men with wives displaying RPL
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Indice:
Méditerranée orientale
langue:
Anglais
Texte intégral:
Int. J. Fertil. Steril.
Année:
2018
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