Detection of different antigens complexed in psoriatic lesions using an immunoperoxidase technique

ABSTRACT

This work was conducted on twenty psoriatic patients, attending the Outpatient Clinic of Dermatology at Assiut University Hospital. Punch biopsies were taken from both involved and uninvolved skin. All the specimens were stained, immunohistochemically using IgG, IgM and IgA antibodies. The presence or absence of immune complex was detected. It was noticed that all psoriatic lesions were stained positive with one or more of the immunoglobulins; in contrast to uninvolved skin of same patient