Combined effect of retinoic acid and basic fibroblast growth factor on maturation of mouse oocyte and subsequent fertilization and development

ABSTRACT

Background: Many autocrine and paracrine elements that are produced within follicular niche have been the focus of much in vitro maturation [IVM] research. The present study was carried out to compare retinoic acid [RA] and basic fibroblast growth factor [bFGF] efficacy on IVM of mouse oocytes, and their further dual consumption to reach an optimal protocol