Acute maternofetal toxoplasmosis: serological and molecular diagnosis

ABSTRACT

Background: Primary toxoplasma infection during pregnancy carries a risk of fetal damage. The most frequent challenge encountered is how to determine if a pregnant woman acquired the acute infection during gestation. We aimed to evaluate the validity of T gondii IgM in a single serum sample versus the detection of IgM seroconversion for the diagnosis of acute maternal toxoplasmosis. In addition to determining the incidence of acute toxoplasmosis among pregnant women and estimating the rate of intrauterine transmission in the Southwestern region of Saudi Arabia