Improvement of liver functional status in diabetic conditions by fresh wheat germ [golden green] supplementation in human patients

ABSTRACT

Fresh wheat germ [Golden Green] was examined for its possible hypoglycemic and hypocholesterolemicinfluences in human patients with several hep1tic complications. A period of four weeks of dietary regimen containing fresh wheat germ flakes [30g daily] was found to be remarkably beneficial, as indicated by significant reduction of serum glucose and lipid profile in diabetic patients. This was also accompanied by slight decrease in patient body weights. Dietary fresh wheat germ feeding also significantly countered other metabolic alterations as revealed by lowering blood urea, creatinine in all patient groups. Obtained results indicated also that incorporation of fresh wheat germ together with the daily nutritional pattern was not changed the daily food intake by all of examined four human groups. All of elevated liver enzymes [ALT, AST and ALP] in diabetic patients with liver complications were significantly lowered. Serum minerals [Fe, Ca, P, Zn and I], hemoglobin, hematocrit, ferritin and detoxifying enzymes [glutathione, catalase, glutathione-S-transferase and glutathione reductase] were significantly [P< 0.05] increased at the end of supplementation course of fresh wheat germ