SEN virus detection in Egyptian patients with chronic hepatitis C and hepatitis C related hepatocellular carcinoma

ABSTRACT

Abstract SEN virus [SENV] is a single stranded DNA virus that belongs to the Circoviridae family. Nine genotypes [A-I] have been identified. Among them, it has been shown that two SENV genotypes [SENV-D and SENV-H] are significantly associated with transfusion-associated non-A-E hepatitis. The exact role of this virus in the pathogenesis of chronic liver disease, including chronic hepatitis and the development of hepatocellular carcinoma [HCC] remains to be established. Aim of work to invesigate the presence of SENV-D and SENV-H viremia among Egyptian patients with chronic hepatitis C and hepatitis C virus [HCV] related hepatocellular carcinoma [HCC] and to assess its possible implications