17 beta-estradiol oxidative stress attenuation and autophagy-induced dopaminergic neuroprotection
Cell Journal [Yakhteh]. 2019; 21 (1): 1-6
Dans Anglais
| IMEMR
| ID: emr-203091
ABSTRACT
Objective:
Degeneration of dopaminergic neurons in the substantia nigra of the brain stem is the main pathological aspect of Parkinson's disease [PD]. 17 beta-estradiol [E2] has neuroprotective effects on substantia nigra, however, the underlined mechanism is not well-known. In this study, we evaluated the neuroprotective effects of E2 in the ovariectomized 6-hydroxydopamine- [6-OHDA] rat model of PD
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Indice:
Méditerranée orientale
langue:
Anglais
Texte intégral:
Cell J. [Yakhteh]
Année:
2019
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