Causes of lymphadenopathy in Egyptian children other than malignancy

ABSTRACT

Fifty children aged 3 to 12 years presented with cervical or inguinal lymph nodes enlargement were selected from Zagazig University Hospitals. They were subjected to routine laboratory examination as well as histopathological and immunopathological studies. The results revealed eosinophilia and intestinal parasites in 80 percent. Besides, pediculosis and flea dermatitis were also demonstrated in 30 and 12 percent respectively. Histopathological studies of the nodal tissues revealed sinus hyperplasia [ten cases], reactive paracortical hyperplasia [30 cases] and necrosis and caseation [ten cases]. Infiltration with eosinophils was demonstrated in the nodal tissues of 40 cases. Immunopathological studies revealed cytotoxic T-cells in all the cases, and helper T lymphocy‚es in only 15 cases. It is concluded that this may give an explanation of some causes of lymphadenopathy in Egyptian children other than malignancy