Diagnostic value of bone marrow examination in haematological and non haematological diseases

ABSTRACT

In this study, 223 bone marrow biopsies and / or aspirations were performed. The main indications for bone marrow examination were diagnosis and management of acute leukaemia [45-20.2%], staging of lymphoma [29-13.1%], evaluation of pancytopenia [31-14.1%], thrombocytopenia [26-11.7%], anaemia [16-7. 2%], pyrexia of unknown origin [PUO] [14-6.1%], lymphadenopathy [16-7. 3%], hepatosplenomegaly [12-5.3%], to exclude metastasis [7-3.2%] and miscellaneous [25-11%]. The most common diagnosis encountered were acute lymphoblastic leukaemia [35-15.7 %], idiopathic thrombocytopenic purpura [13-5.7%], acute myeloid leukaemia [12-5.7%], hyper8plenism [12-5.7%], chronic myeloid leukaemia [12-5.7%], megaloblastic anaemia [7-3.1%] and multiple myeloma [3-1.3%]. It was concluded that bone marrow examination is an important investigation for establishing the diagnosis in many conditions especially haematological neoplasms. The most common indication in this study was to confirm and manage acute leukaemia and the most common diagnosis was acute lymphoplastic leukaemia