Microbiological pattern and risk factors of bacterial colonization in patients with clinically stable boronchiectasis

ABSTRACT

Background: Bronchiectasis, dilatation of bronchi with diameter more than 2 mm is a septic and inflammatory process of the lung, caused by infections and systemic or local defense abnormalities of tracheobronchial tree that may lead to destruction of bronchial wall. Infections usually cause inflammatory reaction and destruction of bronchial wall, this further leads to more disturbance in local defense and a vicious cycle of inflammation and bacterial colonization occurs. These bacteria divided to Potentially Pathogen Microorganism [PPM] or non-PPM. The purpose of this study was to find microbiologic pattern and associated [risk] factors in Iranian population and use of more narrow spectrum antibiotics