Systolic left ventricular functions in patients with acute HBV infection

The present study comprised [42] patents with icteric hepatitis [B] viral infection as a test group together with [8] patients with icteric hepatitis viral infection and negative hepatitis B viral markers. Eight normal subject of matched age and sex were included as a control group. The work revealed a definite myocardial impairment of systolic function in patients with icteric hepatitis B viral infection. The incidence of impairment was high in young males with splenomegaly. The degree of impairment was more in patients with high serum bilirubin, speciall those who developed E.C.G. manifestations that indicate myocardial affection in general. The study recommend a further work searching for the association between myocardial impairment and another viral causes of hepatitis e.g. HCV, Epstein-Barr and Cytomegalovirus. Also, to search for the association between the HB "e" antigenemia as a parameter of HBV replication and the degree of myocardial impairment in acute virus hepatitis