Role of cobalt [II],Copper [II] Nickel [II] and Zinc [II] Metal ions on the pharmacological properties of cephalosporin class of antibiotics ceporex and vetosef

ABSTRACT

Cobalt [II], copper [II], nickel [II] and zinc [II] complexes of cephalosporin class of antibiotics - ceporex and velosef have been synthesised and characterized. The pharmacological assay of the metal-antibiotic complexes have shown to be more antibacterial than the simple antibiotics against bacteria such as streptococcus pyogenes, salmonella arizona, staphylococcus aureus and klebsiella pneumoniae