Conglutination and passive hemagglutination in rapid diagnosis of typhoid fever

ABSTRACT

The efficacy of the enrichment work coagglutination and passive hemagglutination techniques in rapid diagnosis of typhoid fever was studied in parallel with the classical [conventional methods of clot cultures and widal agglutination test], on one hundred clinically suspected cases diagnosed as query enteric fever. Antigen detection in their sera was done by coagglutination [COAG] and clot culture as well as antisalmonella antibody which was detected by passive hemagglutination test [PHAG] and widel test. Analysis of data with reference to confirm typhoid fever cases showed that, Salmonella organism was isolated in 16% of clot cultures. This was correlated closely with widel test [23%] in contrast to PHAG [59%] and COAG [73%]. Thus PHAG and COAG were the superior for serological diagnosis of typhoid fever