Synthesis and reactions of some derivatives of 2-amino-5- [4-pyridyl] -1,3,4-oxadizole

ABSTRACT

By the reaction of 2-amino-5- [4-pyridyl]-1, 3, 4-oxadiazole [1] with aldehydes, the corresponding arylideneimino derivatives [2a-f] were obtained which when reacted with arylisocyanates or benzoylisothiocyanates afforded the corresponding oxadiazolo [3, 2- a]-1, 3, 5- triazines [3 a-g]. The reaction of I with benzoyl- isothiocyanate was also investigated. 3-phenyl 1-6-[4-pyridyl] -1, 2, 4-triazolo [3, 4-b]-1, 3, 4-oxadiazole [6] was obtained on reacting products 4, 9, or 10 with hydrazine hydrate