Inhibitory effects of aqueous extracts of natural products on the crystallization of urinary lithiasis in vitro Part III: Uric acid

ABSTRACT

Relative increase in solubilities of uric acid in aqueous extracts of cucumis melo, eriobotyra japonica, Macrotyloma uniflorum, Pedalium murex and Zea mays were Guantitatively determined in vitro and were found to be 37.2%, 0.8%, 1.3%, 45% and 15.6% respectively. The two major factors which influence the solubilities of uric acid were the presence of metal ions like sodium, magnesium, potassium etc and the adsorption of macromolecules like carbohydrates etc. on the faces of growing crystals