Synthesis of new 2-substituted hydroquinone bis- [dithiocarbazate ester] and there cyclization to corresponding 1,3,4-oxadiazole derivatives

ABSTRACT

Condensation of 2-bromo-, chloro- or nitrohydroquinone-O, O'-diacetyl chloride with methyl or benzyldithiocarbazate gave the corresponding dihydrazide derivatives I-VI. Cyclodehydrosulfurization of the products by thionyl chloride yielded the corresponding di-[1,3,4-oxadiazole] derivatives VII-XII. The structures of all synthesized compounds were confirmed by elemental analysis, IR and PMR spectra