Toxicological effects of pirimiphos-methyl and deltamethrin on albino rats

ABSTRACT

Multi-dose effect of pirimiphos-methyl and deltamethrin on some blood parameters, liver protein content, blood glucose, cholinesterase glutamic oxaloacetic transaminase, glutamic pyruvic transaminase were studied at sub-lethal doses [0.1 LD50 and 0.25 LD50]. The obtained data domenstrated that total leukocytes were significantly increased, with the exception in case of pirimiphos-methyl at 0.1 LD50, but the other blood parameters were not affected. Liver protein and blood sugar were affected apparently after exposure to deltamethrin. The biochemical data showed significant inhibition of cholinesterase activity after exposure to pirimophos-methyl, on the other hand, deltamethrin has no effect, Glutamic oxaloacetic and glutemic pyruvic transaminase activities were markedly increased due to the insecticides treatment