Glucose metabolism in schistosomal hepatic fibrosis

ABSTRACT

Abnormalities in glucose homeostasis in schistosomal hepatic fibrosis was studied in twenty patients of this disease and ten adult normal volunteers used as control. Fasting blood glucose and peripheral utilization were normal. The hepatic glucose output was significantly less in patients than control group. A mild degree of glucose intolerance was demonstrated after the oral and intravenous glucose load. The possible mechanism for this degree of glucose intolerance was discussed