Plasma fibronectin in pre-eclampsia and eclampsia. A prospective controlled study

ABSTRACT

Plasma fibronectin level was determined by radial immunodiffusion technique in 60 patients in labor. 20 of them were normal pregnant women as a control group, 15 patients as a mild preeclampsia, 15 patients with severe preeclampsia and 10 patients having eclampsia. The mean values of plasma fibronectin in mild, severe preeclampsia and eclampsia were significantly higher than that of the control group in both maternal and cord blood plasma. The increased fibronectin levels were considered to be the best predictor and highly sensitive test for preeclampsia