Serum pepsinogen in duodenal ulcer

ABSTRACT

Total serum pepsinogen concentration was determined in 100 patients with endoscopically proven duodenal ulcer and an equal number of age and sex matched controls. Serum pepsinogen levels were within normal limits in 82% cases and raised in 17% cases. Comparison of demographic profile of hyper with normopepsinogenemics showed that patients with raised levels had an early onset of the disease, predominantly belonged to blood group "O" and had a higher frequency of duodenal ulcer perforation than those with normal pepsinogen levels