ST-segment changes as a non-invasive marker of coronary artery patency following streptokinase therapy in acute myocardial infarction
Zagazig Medical Association Journal. 1993; 6 (1): 109-122
Dans Anglais
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ABSTRACT
ST-segment changes and angiocardiographic findings were compared in 42-patients with AMI soon after thrombolysis. The% ST-segment change 3 hours after treatment [In the lead showing the greatest initial ST-segment elevation] was compared with the TIIMI perfusion grades [Thrombolysis in Myocardial Infarction Trial] obtained 24 hours after treatment. Global ejection fraction and regional wall motion were assessed by cineventriculography 14 days later. Prediction of coronary artery pantency by a reduction of >25%in ST-segment elevation 3 hours after thrombolytic treatment had a sensitivily of 96% and specificity of 43%. Where the ST-segment elevation was reduced by > 25% the global ejection fraction was well maintained whether or not the infarct related vessel was patent. In patients with a reduction of <25%in ST-elevation, the ejection fraction was significantly lower and regional wall motion abnormality was more severe. Reduction in ST-elevation of>25% within 3-hours of thrombolysis indicates either a patent infarct related artery or preservation of left ventricular function when the ST-elevation dose not fall by >/= 25%. Persistent coronary artery occlusion is likely [predictive accuracy 86%] and is associated with a lower ejection fraction. These patients may benefit from further treatment or additional interventions:
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Indice:
Méditerranée orientale
Sujet Principal:
Streptokinase
/
Échocardiographie
/
Reperfusion myocardique
/
Traitement thrombolytique
/
Coronarographie
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Zagazig Med. Assoc. J.
Année:
1993
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