Protein and liver enzyme changes in serum as affected by food color additive tartrazine

The effect of food color additive-tartrazine on soluble proteins content, transaminases [ALT and AST] and alkaline phosphatase [ALP] activity in serum male albino rats were studied. Results obtained revealed that levels of serum soluble proteins content was increased insignificantly due to the increase in tartrazine dose. Also, serum transaminases and alkaline phosphatase activities were increased significantly due to tartrazine administration. In addition, the increase in the administration time showed insignificant increase in transaminases, but no change in serum soluble proteins levels and alkaline phosphatase activity was occurred