Detection of chlamydia trachomatis by polymerase chain reaction among infertile couples with antisperm antibodies

ABSTRACT

Chlamydia trachomatis infection is the most common sexual transmitted disease and the role of chlamydial genital infection in the initiation of immune reaction to the sperm and immunological infertility is still controversial. Recently, the development of PCR assays was found to be very effective for the detection of genitourinary chlamydial trachomatis infection. The objective in the present work was to study the possible relation between the chlamydial infection and the development of sperm antibodies. 60 infertile couples with sperm antibodies and 20 fertile couples free from sperm antibodies were the subjects of this study. Detection of chlamydia trachomatis was done by taking samples from endocervical swabs from wives and first voiding urine from husb and s and then tested by PCR. No correlation was found between the chlamydial infection and the development of sperm antibodies. On the other h and, it was observed that male auto immunity to the sperm is more frequent than female iso immunity