Bulletin of Alexandria Faculty of Medicine. 1997; 33 (2): 299-307
Dans Anglais
| IMEMR
| ID: emr-44225
ABSTRACT
In this study, 240 adult healthy albino rats of both sexes were used. They were classified into control and drug-treated groups. Full thickness excised skin wounds were inflicted on the shaved dorsal aspect of the thoracic wall. The mean healing time, rate of wound contraction, the total and the saline soluble collagen concentrations in the healing wound area were measured. Loratadine did not significantly alter any of the wound healing parameters studied. Cimetidine has caused a statistically significant shortening of the mean healing time, acceleration of wound contraction rate, reduction of the total and increase in the saline soluble collagen concentration in the healing wound area 2 and 3 weeks post-wounding
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Indice:
Méditerranée orientale
Sujet Principal:
Rats
/
Peau
/
Cimétidine
/
Loratadine
/
Antihistaminiques des récepteurs H1
/
Antihistaminiques des récepteurs H2
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Bull. Alex. Fac. Med.
Année:
1997
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