Helicobacter pylori among Egyptian patients with chronic liver, diseases a comparative study

ABSTRACT

80 patients subjected to upper gastrointestinal endoscopy were enrolled. They were divided according to their liver status into 2 groups. The 1st group included patients with liver cirrhosis and the 2nd group included patients who had no liver affection. Gallbladder diseases were excluded by abdominal ultrasound examinations. Endoscopic antral mucosal biopsies were used for H. Pylori screening by both culture and urease test, and for histopathological examinations. Both groups were matched as regards age, sex and socioeconomic conditions. Culture was positive in 42.2% and 40.7% of patients in both groups, respectively, [P >0.05]. Urease test showed positive results in 58% and 76.6% in both groups, respectively, [P >0.05]. H. pylori prevalence showed no significant differences between both studied groups as regards age, sex or type of gastric lesions. Furthermore, liver status in patients with chronic liver diseases does not play a role in the distribution of infection. The study showed the high prevalence of H. pylori among Egyptians and the absence of a relation between H. pylori and chronic liver diseases