Melatonin: the assumed latest cure- all drug
New Egyptian Journal of Medicine [The]. 1997; 16 (3): 249-53
Dans Anglais
| IMEMR
| ID: emr-46200
ABSTRACT
This study was carried out to evaluate the hormonal and some biochemical changes which might be caused by administration of melatonin [Mt] daily for five months to 36 albino rats of both sexes. Long-term administration of doses equivalent to human dose range of melatonin caused an increase in testosterone, a decrease in estradiol [E2] levels in males with no change in the levels of both hormones in females, an increase in follicular stimulating hormones [FSH] and luteinizing hormone [LH] and a decrease in prolactin [PRL] levels in both sexes. Serum glutamicoxalo-acetic transaminase [GOT], glutamic- pyruvic transaminase [GPT] and sorbitol dehydrogenase [SDH] showed a significant increase from the third month onwards, while serum urea and creatinine showed a significant increase only at the fifth month
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Indice:
Méditerranée orientale
Sujet Principal:
Prolactine
/
Aspartate aminotransferases
/
Rats
/
Testostérone
/
Urée
/
Hormone lutéinisante
/
Créatine
/
Alanine transaminase
/
Oestradiol
/
L-iditol 2-dehydrogenase
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
New Egypt. J. Med.
Année:
1997
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