Effect of digenous drugs on changes inmorphology and cholesterol level of aorta in early atherosclerotic progression a comparative experimental study

ABSTRACT

Abnormalities in lipid metabolism are among the best known cardiovascular risk factors. Use of medicinal plants in preventing alterations in lipid metabolism has received wide attention by several workers. The present work compared the antihyperlipidaemic effect of guar gum, fenugreek and ginger extracts in hypercholesterolemic rabbits and results compared with Gemfibrozil used as a standard drug. The data pertaining to macroscopic aortic lesions and aortic cholesterol is presented here. The study showed that extracts of guar gum, ginger and fenugreek significantly reduced the sclerotic component and deposition of cholesterol in vessel wall