MRI findings in children with neurofibromatosis-1 [NF - 1]

ABSTRACT

To demonstrate the brain MRl findings in children with NF-1. Patients and Six children, with an age between 1-10 years who have been diagnosed as NF-1 were included in the study. MRl scan was done using T1. T2 Wand post IV. GD DTPT T1 W images. Hyperintense lesions on T2 W images were confined to the globus pallidi in two patients, and associated with sphenoid wing hypoplasia in one patient, and globus pallidi and cerebral peduncles in three patients, including a patient with optic nerve and optic pathway tumor. In globus pallidi, cerebral peduncles and cerebellum white matter in one patients. Due to the high incidence of hyperintense lesions on T2 W images in the brain, the brain findings justify the incorporation of these findings in the diagnostic criteria of NF-l