Endoscopic variceal ligation versus sclerotherapy short term effect on kidney function

ABSTRACT

One hundred patients with liver cirrhosis and history of bleeding esophageal varices were equally divided into two groups. The first group underwent variceal injection sclerotherapy and the second group underwent variceal band ligation. The effect of either procedure on hemolysis and kidney functions were studied. Serum bilirubin, LDH, end creatinine and the percentage of cases who developed hematuria were significantly increased after injection sclerotherapy and creatinine clearance significantly decreased. Renal dysfunction and hematuria were significantly lower in variceal ligation group versus sclerotherapy group. Renal dysfunction and hematuria following sclerotherapy were significnatly more when serum albumin level was below 3 g/dl