Sex Association with HLA-A, -B and -C antigens among bahrainis

ABSTRACT

This is the first study of HLA class I antigens among Bahrainis, which will indicate the HLA -A, -B, and -C amongst Bahrainis in correlation with sex of the population. Six hundred and five Bahrainis were included in the study [303 males 302 females]. The complement-dependent microcytotoxicity [CDC] was used. The study showed that there are unique HLA antigens, which show Bahrainis relation to the Middle East, with the following characteristics of high frequencies A2, Al, A19, A9, Al0, All, B12, B7, B8, B2, B5, B13, Cw4, Cw3, Cw1, Cw2, and Cw6. Some of the antigens were shared with other countries. The results showed that some HLA -A, -B and -C antigens are sex associated