Treatment of urinary tract infection with a daily and unique dose of gentamycin

ABSTRACT

Twenty nine patients with Gram negative urinary tract infection have received gentamicin in a single daily dose of 2,5 mg per kilogram of body weight for 10 days. Follow up is based on bacteriologic and biologic data and on dosage of gentamicin. The mean values of gentamicin levels obtained in blood and urine are efficient and non toxic. In 14% of cases, failure of treatment is due to a local cause of urinary tract infection. A single daily dose of gentamicin is efficient and non toxic if adapted to the patient's weight