Vitreous / blood concentration ratio in drug overdoses an experimental study
MJFCT-Mansoura Journal of Forensic Medicine and Clinical Toxicology. 1999; 7 (1): 157-68
Dans Anglais
| IMEMR
| ID: emr-51848
ABSTRACT
Serum and vitreous concentrations in three drug overdoses [phenobarbitone,morphine and theophylline] were measured in albino rats after 1, 2, 4 and 12 hours of i.p. injection. Vitreous/blood ratio was determined for every drugoverdose. It was found that this ratio remained constant regardless of thetime passed since injection. The study demonstrated that vitreous is a cleanbiological fluid that can be used for the detection of drug overdose by EMIT and can predict the blood concentration of the drug as long as vitreous/bloodratio is known
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Indice:
Méditerranée orientale
Sujet Principal:
Rats
/
Théophylline
/
Surveillance des médicaments
/
Technique EMIT
/
Morphine
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mansoura J. Forensic Med. Clin. Toxicol.
Année:
1999
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