Study of serum interleukin-1B and left ventricular function in patients with essential hypertension

ABSTRACT

This study was done on 40 patients with essential hypertension [group I], 25 patients with familial hypercholesterolemia [FH] [group II] and 20 normal control subjects [group III]. All cases were subjected to complete clinical examination including mean arterial blood pressure, complete blood picture, blood urea, serum creatinine, fasting blood sugar, two-hour postprandial, liver function tests, serum cholesterol, triglycerides, HDL, LDL, lipoprotein [a], ECG, echocardiography and serum IL-1 B. From the results obtained, it was concluded that high level of IL-1 B may be an additional risk factor for atheromatosis in patients with essential hypertension and blocking. The activity of this cytokine may be considered as a therapeutic possibility