Analgesic effects of propofol on orthopedics' day surgeries.

ABSTRACT

The present study was designed to assess analgesic effects of propofol on orthopedics' day surgeries. 150 adult patients undergoing orthopedics' day surgeries were randomly divided into 3 groups and allocated to receive either propofol, ketamine or thiopenal for induction and maintaining anesthesia, after premedication by 1 [micro] g/kg of fentanyl. To evaluate pain and to detect painful stimulation, parameters such as heart rate, systolic and diastolic arterial blood pressure, respiratory rate, pupil size, perspiration, muscle movement, awareness in recovery room, recall during surgery and satisfaction from anesthesia were used. Changes in these parameters were significantly greater in propofol group. We concluded that propofol does not have analgesic effects during anesthesia and must be accompanied by an analgesic like fentanyl or alfentanil and can be used by intravenous bolus method: