Non-penetrating trabeculectomy with adjunctive mitomycin C in open angle glaucoma

ABSTRACT

The aim of this work was to evaluate and compare the results of non- penetrating trabeculectomy [NPT] alone or with the use of adjunctive mitomycin C [MMC] in primary open glaucoma. Twenty-eight eyes of 28 patients with uncontrolled primary open angle glaucoma were randomly assigned either to NPT alone [group 1] or with the application of MMC [group 2]. The cases were followed up for one-year. Success rate was defined as an intraocular pressure [IOP] of 21 mmHg or less without glaucoma medications. The rates of success at the final follow up period were 78.5% in the NPT without MMC [group 1] versus 92.8% in the NPT with MMC [group 2]. In conclusion, NPT with the application of MMC is an effective technique in controlling IOP in primary open angle glaucoma with avoiding the potential complications of standard trabeculectomy