Role des lysosomes dans le comportement intracellulaire d'elements mineraux: cas du lanthane

ABSTRACT

The subcellular localization of lanthane was studied using two microanalytic methods.1]The election microprobe method showed that lanthane is concentrated in the lysosomes of the hepatocytes and the spleen associated with phosphorus. 2]The ion microanalysis showed that lanthane is selectively precipitated in the lysosomes of the enterocytes opical part. This mechanism of selective precipitation initially privents the diffusion of this toxic element in organism and then permits its elimination digestively after desquamation of enterocytes in apoptose in the interstinal lumen