Bone marrow suppression in chronic hepatitis C

ABSTRACT

Various extrahepatic manifestations of chronic viral infections are known. Here are described four cases of chronic hepatitis C in which marrow suppression was found on initial diagnosis. The diagnosis was made with standard criteria of elevated ALT, with positive anti HCV and presence of HCV RNA. No anti viral treatment with Interferon or Ribavirin was possible in these cases. Only supportive treatment was feasible. All these patients died because of complications of chronic liver disease