Stability study of some complexes of sulphamethoxazole
Journal of Drug Research of Egypt. 1985; 16 (1-2): 175-80
Dans Anglais
| IMEMR
| ID: emr-5853
ABSTRACT
The interaction of certain transition metal ions Cu [II], Zn [II], Ni [II], Co [II] and Mn [II] with sulphamethoxazole have been studied in 50% ethanol-water medium at 30 and different ionic strengths following Irving-Rossitti pH titration technique. The proton-ligand and metal-ligand formation constants [log K[H1] and log beta2] calculated, show the order of stability as [Cu [II] > [Zn [II] > Ni [II] > Co [II] > [Mn [II]. Thermodynamic parameters [delta G, delta H and delta S], calculated at 30 and 0.1 M [KC1] ionic strength
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Indice:
Méditerranée orientale
Sujet Principal:
Interactions médicamenteuses
/
Stabilité de médicament
langue:
Anglais
Texte intégral:
J. Drug Res. Egypt
Année:
1985
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