Neurohormonal changes in medical students during academic srtess
Annals of Saudi Medicine. 2005; 25 (1): 36-40
Dans Anglais
| IMEMR
| ID: emr-69771
ABSTRACT
Academic stress is a good model of psychological stress in humans and is thus useful for studying psychoneurohormonal changes. The aim of the current study was to examine the effect of academic examination stress on activation of the hypothalamus-autonomic nervous system [HANS] and the hypothalamic-pituitary-adrenocortical [HPA] axis, through the measurements of changes in neuro-hormones during final exams as compared to the pre-exam baseline. Forty-eight first- and second-year female medical students participated. Plasma leptin, neuropeptide Y [NPY], nitrite, nitrate, andrenomedullin, cortisol and adrenocorticotropic hormone [ACTH] were measured at baseline and during final examinations. Plasma levels of cortisol, ACTH, NPY, adrenomedullin, nitrite and nitrate increased during times of academic stress as compared to baseline levels. However, only plasma leptin level was decreased during the academic stress as compared to baseline, probably through a negative feedback mechanism resulting from sympathetic stimulation. The results indicate that both the HANS and HPA are involved in this type of stress and both are activated at the same time. Academic stress induced significant neurohormonal changes. Leptin, NPY, nitrite, nitrate, adrenomedullin, cortisol and ACTH can be considered part of a complex mosaic model of the neuroendocrine system during academic stress
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Stress physiologique
/
Étudiant médecine
/
Neuropeptide Y
/
Hydrocortisone
/
Hormone corticotrope
/
Agents neuromédiateurs
/
Leptine
/
Nitrates
/
Nitrites
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Ann. Saudi Med.
Année:
2005
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS