Asymptomatic bacteriuria in type 2 diabetic women in Iran

ABSTRACT

This study was performed to evaluate the prevalence and risk factors of asymptomatic bacteriuria [ASB] in women with type 2 diabetes mellitus in Iranian population. Between March 2003 and December 2003, 202 nonpregnant women with diabetes type 2 who were between 31 to 78 years old and had no abnormalities of the urinary tract system were included. We defined ASB as the presence of at least 105 colony-forming units/ml of 1 or 2 bacterial species, in two separated cultures of clean-voided midstream urine. All the participants were free from any symptoms of urinary tract infection [UTI]. Risk factors for developing bacteriuria was assessed and compared in participants with and without bacteriuria. In this study, the prevalence of ASB was 10.9% among diabetic women. E.coli was the most prevalent microorganism responsible for positive urine culture. Most of the isolated microorganisms were resistant to Co-trimoxazole, Nalidixic acid and Ciprofloxacin. Pyuria [P<0.001] and glucosuria [P<0.05] had meaningful relation with bacteriuria but no association was evident between age [P<0.45], duration of diabetes [P<0.09], macroalbuminuria [P<0.10] and HbA1c level [P<0.75], and the presence of ASB. The prevalence of ASB is more prevalent in women with type 2 diabetes, which pyuria and glucosuria can be considered as risk factors in this regard. Routine urine culture can be recommended for diabetic women even when there is not any urinary symptom