Unexplained recurrent abortion and diminished ovarian reserve

ABSTRACT

To Determin the incidence of diminished ovarian reserve in unexplained recurrent abortion. among 116 women with complaint of recurrent abortion who referred to Ghaem hospital, after evaluation, 25 women with unexplained recurrent abortion were chosen as the test group and the control group [n=25] were women with a history of normal pregnancy. Mean age, day 3 serum FSH and E2 levels, presence or absence of a history of infertility and menstrual cycle lengths were compared between two groups. Day 3 FSH and E2 levels were higher in the unexplained recurrent abortion group compared with the control group [61% VS 16%] P <0.005. Other factors did not differ between two groups. Women with unexplained recurrent abortion have a greater incidence of elevated day 3 serum FSH and E2 levels than do women with a normal pregnancy history. Therefore diminished ovarian reserve may contribute to recurrent pregnancy loss and should be considered as a part of the work - up for unexplained recurrent abortion