Synthesis of some naphthalene -sulphonohydrazides and related compounds of potential biological activity

ABSTRACT

In a search for new pest control agents, the following naphthalene sulphonohydrazides have been prepared naphthalene-1-sulphonyl hydrazide, naphthalene-2-sulphonyl hydrazide, 4-chloronaphthalene-1-sulphonyl hydrazide and naphthalene-1, 5-bis-sulphonyl hydrazide. The hydrazides have been converted into a number of derivatives [e.g. hydrazones, and their N-methyl and s-benzyl-iso-thiuronium derivatives]. The compounds were characterised by their ultraviolet, infrared and nuclear magnetic resonance, and these are briefly discussed. The insecticidal activity of these compounds was screened against cotton leaf worm