Evaluation of the efficacy of persica mouth wash on the healing of recurrent aphthous stomatitis [RAS]

ABSTRACT

Recurrent aphthous stomatitis is one of the most common Diseases of oral mucosa. In spite of its popularity and severity of pain, it dosen't have a routine treatment method. Because of side effects of different chemical drugs, recently, herbal drugs had been used in treatment of these lesions causing a decrease in pain and burning. The purpose of this study was to evaluate the efficacy of persica mouth wash in controlling the pain and decreasing the healing period of Recurrent Aphthous Stomatitis [RAS]. In this double blinded clinical trial study, 24 patients with Recurrent Aphthous Stomatitis without any systemic Diseases were chosen. Each patient was considered as study sample for one time period and then as control for another time period. The patients used persica mouth wash and placebo [as mouth wash] alternatively. A visual Analogue scale [VAS] was used to evaluate the pain and burning of the lesions. For data analysis, chi square, t-test, and spss program was used. There was a significant difference in pain reduction [62.5 and 20.8 percent] and burning reduction [70.8 and 25 percent] between experimental and control groups. There was no significant difference in healing period reduction between the two groups. In this study persica mouth wash as a herbal drug had a positive effect on pain and Burning of the Aphthous lesions. This mouth wash was not effective in reducing the healing period of these lesions. This study suggests the use of persica mouthwash alone or in combination with other drugs to decrease pain and burning of Aphthous lesions