Pattern on blood levels of erythropoietin patients and proinflammatory cytokines in anemic on regular hemodialysis
Medical Journal of Teaching Hospitals and Institutes [The]. 2005; (46): 25-32
Dans Anglais
| IMEMR
| ID: emr-73227
ABSTRACT
The objective of this study was to assess the blood levels of cytokines as interleukin-1 B [IL-1 B], interleukin-6 [IL-6] and Epo in anemic patients on regular hemodialysis [HD] and evaluate their relation to the anemic status of those patients. Sera levels of IL-1 B, IL-6 and Epo were measured by ELISA technique in 40 patients on regular HD. The patients were compared with 20 healthy controls. A statistically significant decrease of serum Epo level and a statistically significant elevation for the sera levels of IL-1 B and IL-6 were detected in the patients compared with the controls. A Positive correlation between IL-1 B and IL-6 was detected. Statistically significant negative correlations between IL-1 B and hemoglobin [Hb] level were observed. Also, statistically significant negative correlations between IL-6 and Hb were observed. Hence, these cytokines would be involved in the pathophysiology of end stage renal disease [ESRD] anemic patients
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Indice:
Méditerranée orientale
Sujet Principal:
Test ELISA
/
Cytokines
/
Érythropoïétine
/
Interleukine-6
/
Interleukine-1
/
Anémie
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Med. J. Teach. Hosp. Inst.
Année:
2005
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