Hyperlipidemia and severity of the nephrotic syndrome

ABSTRACT

The changes in the concentration of serum lipids in nephrotic syndrome [N.S.] have been studied on thirty eight patients. Percutaneous renal biopsy was performed on all of them. The results showed that [1] Fredrickson type II b hyper lipoproteinemia was the predominant among those patients [65.8%]. [2] None of the patients showed type I or type V hyper lipoproteinemia, [3] an inverse correlation was found between the ratio of low density lipoprotein cholesterol to high density lipoprotein cholesterol and the severity of the disease as indicated by the degree of hypoalbuminemia, [4] No correlation could be found between changes in serum lipids and the cause of N.S. as assessed by renal histopathological study