[ sarcoidosis]

ABSTRACT

Sarcoidosis is a multisystemic granulomatosis seen mainly in the young adult. This is a retrospective study which evaluated 35 cases of sarcoidosis confirmed histologically, during periods from 1985 to 1999. In this study, 88.57% of patients were female with a mean age of 47.5 years old. The main complaint was often a peripheral node lesion followed by an ocular lesion. This clinical study had a very polymorphic presentation. The endothoracic lesions were largely predominant [94.28%], followed by extra thoracic lesions such as cutaneous lesions [big nodules and erythema nodosum], ocular lesions [25.7%], represented by anterior uveitis [4 cases], posterior uveitis [2 cases] and one case of panuveitis. Lymphatic node lesions were present in 63% of cases. The articular involvement was mainly made of inflammatory arthralgia. The bone lesions seen in 5 cases were made of sarcoid dactylitis confirmed histologically in 3 cases. We observed one case of sarcoidosis associated to spondylarthropathy. Prednisone was indicated in 27 patients at a dose of 0.5 to 1mg/kg/day, leading to a good recovery in 58.33 of cases. The mean follow-up was 20 months. Sarcoidosis in Morocco seems to be rare. The association of sarcoidosis and spondylarthropathy was rarely described. Posterior uveitis was present in this series