Role of glyceryl trinitrate 0.2% ointment in the wound healing post open haemorrhoidectomy

ABSTRACT

Open haemorrhoidectomy may be associated with delayed wound healing which increase the postoperative pain and discomfort. This study assessed the effect of glyceryl trinitrate [GTN] 0.2% ointment on the wound healing after open haemorrhoidectomy. Sixty patients, 41 [68.3%] males and 19 [31.7%] females, aged between 25- 60 years [median 42 years] presented with symptomatic haemorrhoids included in this study. The patients divided into two groups; group I, 30 patients received the GTM ointment post open haemorrhoidectomy, and group II, 30 patients received no local medications postoperative. There were no statistically differences in sex, age, degree and number of haemorrhoids, duration of surgery and hospital stay. 13 patients of the GTN group showed complete epithelialization 3 weeks after surgery while only 6 patients showed this in the control group. There were no complications requiring stoppage of the ointment. GTN 0.2% ointment can be used post-open haemorrhoidectomy to accelerate the wound healing