Analysis of kidney stones by FTIR spectroscopy

ABSTRACT

This study was carried out to investigate the composition and type of kidney stones in our population. Analytical study. Kidney stones recovered from patients of different hospitals of Hyderabad and adjoining areas [Liaquat University Hospital Jamshoro, Memon Charitable Hospital Hyderabad, Wali Bhai Rajputana Hospital Hyderabad, Naseem Medical Center Hyderabad and Isra University Hospital, Hyderabad, Sindh] during 2005 - 2006. A total of 58 kidney stone samples were collected randomly and analyzed for composition by Fourier Transform Infrared Spectroscopy [FTIR]. Of 58 kidney stone samples, 37.9% were pure calcium oxalate stones, 3.4% were uric acid, 44% calcium oxalate + uric acid, 3.4% calcium oxalate + aspartate and 10.3% were magnesium ammonium phosphate. The IR bands were compared with standards. Gender wise comparison revealed that majority of the stones [68.9%] analyzed were recovered from male patients. Whereas, stones recovered from females were only 31.1%. Age wise comparison data disclosed that age range for the presentation of kidney stone disease was 15-29 years. Calcium oxalate + uric acid stones are commonly found in patients of Hyderabad and adjoining areas